Role of Hal5p protein kinase under ethanol stress in Saccharomyces cerevisiae

Yeast Saccharomyces cerevisiae is one of the simplest eukaryotic model organisms to study various parameters ethanol tolerance and has attracted a huge consideration for cost-conscious production bioethanol by fermentation soluble sugars. Ethanol crucial efficient from S. cerevisiae. In this study, we examined role HAL5 protein kinase in comparing cell growth, survival, stress responses wild-type, hal4,5 mutant, Hal5p overexpressed strains under 10 % (V/V) stress. Our findings suggest that overexpression enhances improving cellular ethanol-induced stress, including trehalose accumulation, reactive oxygen species (ROS) management, glutathione homeostasis, lipid peroxidation, carbonyl contents.